Opigolix (ASP1707) | GnRH antagonist | Probechem Biochemicals

Chemical Structure : Opigolix

Opigolix (ASP-1707, ASP1707)

Catalog No.: PC-61391Not For Human Use, Lab Use Only.

Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.

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Biological Activity

Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.

ASP1707 suppresses the pituitary–gonadal axis, suggesting a therapeutic potential to ameliorate pain associated with endometriosis.

Physicochemical Properties

M.Wt	544.505
Formula	C25H19F3N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R)-N-{5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2Hbenzimidazol-2-ylidene)-3-oxopropanoyl]-2-fluorobenzene-1-sulfonyl}-2-hydroxypropanimidamide

References

1. D'Hooghe T, et al. Hum Reprod. 2019 May 1;34(5):813-823.

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Opigolix (ASP-1707, ASP1707)

Biological Activity

Physicochemical Properties

References

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