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Opigolix

Chemical Structure : Opigolix

CAS No.: 912587-25-8

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Opigolix (ASP-1707, ASP1707)

Catalog No.: PC-61391Not For Human Use, Lab Use Only.

Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Opigolix (ASP-1707, ASP1707) is a potent gonadotrophin releasing hormone (GnRH) antagonist, significantly reduces endometriosis-associated pelvic pain.
    ASP1707 suppresses the pituitary–gonadal axis, suggesting a therapeutic potential to ameliorate pain associated with endometriosis.

    Physicochemical Properties

    M.Wt 544.505
    Formula C25H19F3N4O5S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (2R)-N-{5-[3-(2,5-difluorophenyl)-2-(1,3-dihydro-2Hbenzimidazol-2-ylidene)-3-oxopropanoyl]-2-fluorobenzene-1-sulfonyl}-2-hydroxypropanimidamide

    References

    1. D'Hooghe T, et al. Hum Reprod. 2019 May 1;34(5):813-823.

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