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Orexin Receptor agonist (R)-2

Chemical Structure : Orexin Receptor agonist (R)-2

CAS No.: 2639149-58-7

Orexin Receptor agonist (R)-2

Catalog No.: PC-20561Not For Human Use, Lab Use Only.

Orexin Receptor agonist (R)-2 is a potent, dual orexin receptor (OX1R and OX2R) agonist with EC50 of 13.5 nM for OX1R and 0.579 nM for OX2R.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Orexin Receptor agonist (R)-2 is a potent, dual orexin receptor (OX1R and OX2R) agonist with EC50 of 13.5 nM for OX1R and 0.579 nM for OX2R.

Physicochemical Properties

M.Wt 565.69
Formula C30H35N3O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

O=C(N(C1CCCC2=C1C=C(NS(=O)(C3=CC(C(N(C)C)=O)=CC=C3OC)=O)C=C2)C)CC4=CC=CC(OC)=C4

References

1. Patent WO2021065893 A1.

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