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Chemical Structure : Orpinolide
Catalog No.: PC-22607Not For Human Use, Lab Use Only.
Orpinolide is a synthetic withanolide analog with potent antileukemic properties, directly targets oxysterol-binding protein OSBP, disrupts Golgi homeostasis via a mechanism that requires active phosphatidylinositol 4-phosphate (PtdIns4P, PI4P) signaling at ER-Golgi membrane interface.
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Orpinolide is a synthetic withanolide analog with potent antileukemic properties, directly targets oxysterol-binding protein OSBP, disrupts Golgi homeostasis via a mechanism that requires active phosphatidylinositol 4-phosphate (PtdIns4P, PI4P) signaling at ER-Golgi membrane interface.
| M.Wt | 483.69 | |
| Formula | C30H45NO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Marko Cigler, et al. Nat Chem Biol. 2024 Jun 21. doi: 10.1038/s41589-024-01614-4.
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