Chemical Structure : Orteronel
CAS No.:
566939-85-3
Orteronel
(TAK-700, TAK700)
Catalog No. : PC-42626Not For Human Use, Lab Use Only.
Orteronel (TAK-700) is a highly selective CYP17A1 (17,20-lyase) inhibitor with IC50 of 17 nM for human 17,20-lyase.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4262601
Biological Activity
Orteronel (TAK-700) is a highly selective CYP17A1 (17,20-lyase) inhibitor with IC50 of 17 nM for human 17,20-lyase.
Physicochemical Properties
M.Wt
307.3465
Formula
C18H17N3O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-Naphthalenecarboxamide, 6-[(7S)-6,7-dihydro-7-hydroxy-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-
References
1. Kaku T, et al. Bioorg Med Chem
2. Yamaoka M, et al. J Steroid Biochem Mol Biol
3. Dreicer R, et al. Clin Cancer Res
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