Chemical Structure : Osilodrostat
CAS No.: 928134-65-0
Catalog No.: PC-38385Not For Human Use, Lab Use Only.
Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase (CYP11B2) with IC50 of 2.5 and 0.7 nM, respectively.
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M.Wt | 227.237 | |
Formula | C13H10FN3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile |
1. Amar L, et al. Hypertension. 2010 Nov;56(5):831-8.
2. Calhoun DA, et al. Circulation. 2011 Nov 1;124(18):1945-55.
3. Bertagna X, et al. J Clin Endocrinol Metab. 2014 Apr;99(4):1375-83.
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