Osilodrostat (LCI 699) | CYP11 B2 inhibitor

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-Osilodrostat

Chemical Structure : Osilodrostat

CAS No.: 928134-65-0

Osilodrostat (LCI699, LCI-699)

Catalog No.: PC-38385Not For Human Use, Lab Use Only.

Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively.

Packing	Price	Stock
25 mg	$188	In stock
50 mg	$328	In stock
100 mg	$548	In stock
1 g		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Osilodrostat (LCI 699) is a potent, orally active inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 of 2.5 and 0.7 nM, respectively.
Osilodrostat (LCI 699) reduces serum aldosterone, and has benefit in the treatment of hypertension.

Physicochemical Properties

M.Wt	227.237
Formula	C13H10FN3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-4-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl)-3-fluorobenzonitrile

References

1. Amar L, et al. Hypertension. 2010 Nov;56(5):831-8.

2. Calhoun DA, et al. Circulation. 2011 Nov 1;124(18):1945-55.

3. Bertagna X, et al. J Clin Endocrinol Metab. 2014 Apr;99(4):1375-83.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

Osilodrostat (LCI699, LCI-699)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.