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Oxymatrine

Chemical Structure : Oxymatrine

CAS No.: 16837-52-8

Oxymatrine

Catalog No.: PC-24069Not For Human Use, Lab Use Only.

Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway, also is a TLR2 agonist that directly bind to toll-like receptor 2 (TLR2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Oxymatrine, an alkaloid from Sophora flavescens Alt. with anti-inflammatory, antifibrosis, and antitumor effects, inhibits the iNOS expression and TGF-β/Smad pathway, also is a TLR2 agonist that directly bind to toll-like receptor 2 (TLR2).

Physicochemical Properties

M.Wt 264.37
Formula C15H24N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide

References

1. Wu C, et al. Mol Med Rep. 2015 Jun;11(6):4129-34.

2. Ni C, et al. J Pharm Anal. 2025 Jan;15(1):101054.

3. Fan H, et al. Mediators Inflamm. 2009;2009:704706.

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