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P23E02

Chemical Structure : P23E02

CAS No.: 1233078-56-2

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P23E02

Catalog No.: PC-22983Not For Human Use, Lab Use Only.

P23E02 is a small molecule inhibitor of SARS-CoV-2 viral protein Nsp1-40S ribosomal subunit (stem-loop 1, SL1) interaction with IC50 of 2.26 uM, exhibits antiviral efficacy against various sarbecoviruses.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

P23E02 is a small molecule inhibitor of SARS-CoV-2 viral protein Nsp1-40S ribosomal subunit (stem-loop 1, SL1) interaction with IC50 of 2.26 uM, exhibits antiviral efficacy against various sarbecoviruses.

Physicochemical Properties

M.Wt 342.39
Formula C23H18O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(dibenzo[b,d]furan-4-yl)-2,2-dimethyl-2H-chromen-7-ol

References

1. Wan Gi Byun, et al. Angew Chem Int Ed Engl. 2024 Aug 12:e202405472.

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