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PANK-IN-2

Chemical Structure : PANK-IN-2

CAS No.: 902614-04-4

PANK-IN-2 (Pantothenate kinase-IN-2)

Catalog No.: PC-28331Not For Human Use, Lab Use Only.

PANK-IN-2 is a poten tinhibitor of Pantothenate kinase (PANK) with IC50 of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3 respectively in radiochemical enzyme assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PANK-IN-2 is a poten tinhibitor of Pantothenate kinase (PANK) with IC50 of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3 respectively in radiochemical enzyme assays.

Physicochemical Properties

M.Wt 391.49
Formula C21H21N5OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(2,4-Dimethylpyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidin-3-yl)-N-(3-(methylthio)phenyl)propanamide

References

1. Sharma LK, et al J Med Chem. 2015 Feb 12;58(3):1563-8.

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