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PANK-IN-3

Chemical Structure : PANK-IN-3

CAS No.: 3127186-06-2

PANK-IN-3 (Pantothenate kinase-IN-3)

Catalog No.: PC-28332Not For Human Use, Lab Use Only.

PANK-IN-3 is a high-affinity, selective inhibitor of PANK3 (Pantothenate kinase 3) with Ki of 4.2 nM, 104-fold selective over PanK1β.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PANK-IN-3 is a high-affinity, selective inhibitor of PANK3 (Pantothenate kinase 3) with Ki of 4.2 nM, 104-fold selective over PanK1β.

Physicochemical Properties

M.Wt 441.91
Formula C18H21ClFN5O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-(2-(4-(6-chloropyridazin-3-yl)-piperazin-1-yl)-2-oxoethyl)-2-fluorophenyl)-ethanesulfonamide

References

1. Coker AL, et al. J Med Chem. 2026 Mar 12;69(5):6004-6013.

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