PCiB-1

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Chemical Structure : PCiB-1

Catalog No.: PC-21863Not For Human Use, Lab Use Only.

PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division.

Physicochemical Properties

M.Wt	316.34
Formula	C11H10F2N4OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2,4-difluorophenyl)-3-(3-(ethylthio)-1,2,4-thiadiazol-5-yl)urea

References

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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PCiB-1

Biological Activity

Physicochemical Properties

References

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