PCiB-1

Chemical Structure : PCiB-1

Catalog No.: PC-21863Not For Human Use, Lab Use Only.

PCiB-1 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 7.0 uM, inhibits phosphatidylethanolamine (PE) transport from mitochondria to the endoplasmic reticulum (ER), induces mitochondrial division.

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Biological Activity

Physicochemical Properties

M.Wt	316.34
Formula	C11H10F2N4OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2,4-difluorophenyl)-3-(3-(ethylthio)-1,2,4-thiadiazol-5-yl)urea

References

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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PCiB-1

Biological Activity

Physicochemical Properties

References

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