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PCiB-2

Chemical Structure : PCiB-2

CAS No.: 731816-59-4

PCiB-2

Catalog No.: PC-21864Not For Human Use, Lab Use Only.

PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PCiB-2 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 2.0 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2, induces mitochondrial division.

Physicochemical Properties

M.Wt 388.26
Formula C15H15Cl2N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(3-(3,4-dichlorophenyl)ureido)-N,N-dimethylbenzenesulfonamide

References

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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