PCiB-3

Chemical Structure : PCiB-3

Catalog No.: PC-21865Not For Human Use, Lab Use Only.

PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2.

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Biological Activity

PCiB-3 is a small molecule inhibitor capable of inhibiting phosphatidylcholine (PC) biogenesis with IC50 of 0.4 uM, inhibits the phosphatidylethanolamine (PE) methyltransferase activity of Cho2.
PCiB-3 affects phospholipid composition in vivo.
PCiB-3 induces mitochondrial division.

Physicochemical Properties

M.Wt	468.88
Formula	C18H13ClN2O7S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(((4-chlorophenyl)sulfonyl)oxy)-3-nitro-N-phenylbenzenesulfonamide

References

1. Hiroya Shiino, et al. iScience. 2024 Feb 10;27(3):109189.

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PCiB-3

Biological Activity

Physicochemical Properties

References

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