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PD166793

Chemical Structure : PD166793

CAS No.: 199850-67-4

PD166793 (PD-166793)

Catalog No.: PC-22480Not For Human Use, Lab Use Only.

PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PD166793 (PD-166793 ) is a selective, orally active broad spectrum inhibitor of MMPs with IC50 of 4, 7, and 8 nM for MMP-2, MMP-3 and MMP-13, inhibits MMP-1, MMP-7 and MMP-9 with IC50 of 6-8 uM.

Physicochemical Properties

M.Wt 412.30
Formula C17H18BrNO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((4'-bromo-[1,1'-biphenyl]-4-yl)sulfonyl)-L-valine

References

1. McElmurray JH 3rd, et al. J Pharmacol Exp Ther. 1999 Nov;291(2):799-811.

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