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PDEδ-IN-99

Chemical Structure : PDEδ-IN-99

CAS No.: 1841464-21-8

PDEδ-IN-99

Catalog No.: PC-61995Not For Human Use, Lab Use Only.

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ with Kd of 8±4 nM..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ with Kd of 8±4 nM.

Physicochemical Properties

M.Wt 447.514
Formula C25H26FN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-fluorophenethyl)-4-(4-methyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide

References

1. Murarka S, et al. Chemistry. 2017 May 2;23(25):6083-6093.

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