PDEδ-IN-99 | PDE6D-RAS inhibitor | Probechem Biochemicals

Chemical Structure : PDEδ-IN-99

CAS No.: 1841464-21-8

Catalog No.: PC-61995Not For Human Use, Lab Use Only.

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ (PDE6D) with Kd of 8 nM.

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Biological Activity

PDEδ-IN-99 is a novel potent K-Ras-PDEδ inhibitor that binds to the farnesyl binding pocket of PDEδ (PDE6D) with Kd of 8 nM.

M.Wt	447.514
Formula	C25H26FN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-fluorophenethyl)-4-(4-methyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide

1. Murarka S, et al. Chemistry. 2017 May 2;23(25):6083-6093.