Catalog No.: PC-42958Not For Human Use, Lab Use Only.
PEAQX (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM).
PEAQX tetrasodium hydrate (NVP-AAM077) is a potent, selective, NR2A-preferring NMDA receptor antagonist with IC50 of 270 nM (NR1A/2A), >100-fold selectivity over NR1A/2B receptor (IC50=29,600 nM).
PEAQX (NVP-AAM077) shows high binding affinity for NMDA receptors (IC50=8 nM), induces social facilitation in adolescent male rats (1.25, 3.75mg/kg).
PEAQX (NVP-AAM077) enhances locomotor activity in response to PCP challenge in vivo.
