Chemical Structure : PF-06282999
CAS No.:
1435467-37-0
PF-06282999
(PF06282999;PF 06282999)
Catalog No. : PC-45604Not For Human Use, Lab Use Only.
PF-06282999 is a potent, highly selective and irreversible inhibitor of myeloperoxidase (MPO) with Kinact/KI of 116000 M-1s-1.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4560401
Biological Activity
PF-06282999 is a potent, highly selective and irreversible inhibitor of myeloperoxidase (MPO) with Kinact/KI of 116000 M-1s-1.
Physicochemical Properties
M.Wt
325.7707
Formula
C13H12ClN3O3S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 32 mg/mL
Chemical Name/SMILES
1(2H)-Pyrimidineacetamide, 6-(5-chloro-2-methoxyphenyl)-3,4-dihydro-4-oxo-2-thioxo-
References
1. Ruggeri RB, et al. J Med Chem.
2. Dong JQ, et al. Drug Metab Dispos.
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