Chemical Structure : PF-06424439
CAS No.:
1469284-78-3
PF-06424439
(PF06424439)
Catalog No. : PC-38095Not For Human Use, Lab Use Only.
PF-06424439 (PF06424439) is a potent, selective, orally acitve DGAT2 inhibitor with IC50 of 14 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-3809501
Biological Activity
PF-06424439 (PF06424439) is a potent, selective, orally acitve DGAT2 inhibitor with IC50 of 14 nM.
Physicochemical Properties
M.Wt
39.94
Formula
C22H26ClN7O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(R)-(1-(2-(1-(4-chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone
References
1. Futatsugi K, et al. J Med Chem.
2. Pabst B, et al. Biochemistry.
3. Takemoto K, et al. Physiol Rep.
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