| Cat. No. |
Product Name |
Information |
| PC-73223 |
BMS-963272
MGAT2 inhibitor
|
BMS-963272 is a potent, selective MGAT2 inhibitor with IC50 of 7.1 and 18 nM for human and mouse MAGT2, respectively. |
| PC-72624 |
PF-06865571
DGAT2 inhibitor
|
PF-06865571 (Ervogastat, PF 06865571) is a potent, selective diacylglycerol acyltransferase DGAT2 inhibitor with IC50 of 17.2 and 833 nM for human and rat DGAT2, respectively. |
| PC-38095 |
PF-06424439
DGAT2 inhibitor
|
PF-06424439 (PF06424439) is a potent, selective, orally acitve DGAT2 inhibitor with IC50 of 14 nM. |
| PC-62635 |
GSK2973980A
|
GSK2973980A is a potent and selective DGAT1 inhibitor with IC50 of 3 nM, exhibits >2,900-fold selectivity over human DGAT2, ACAT1 and ACAT2 (IC50>10 uM). |
| PC-42121 |
A-922500
DGAT-1 inhibitor
|
A-922500 (A922500) is a potent, selective and orally bioavailable DGAT-1 inhibitor with IC50 of 9 and 22 nM against human and mouse DGAT-1, respectively. |
| PC-45795 |
T-863
|
T-863 is a potent and selective, cell-permeable DGAT1 inhibitor that binds to the oleoyl-CoA binding pocket of DGAT1 with IC50 of 17 nM in TLC assay. |
| PC-21285 |
PF-07202954
DGAT2 inhibitor
|
PF-07202954 is a potent, selective next-generation DGAT2 inhibitor with IC50 of 10 nM (hDGAT2). |
| PC-21222 |
TP-020
MGAT2 inhibitor
|
TP-020 is a potent, selective, orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. |
| PC-21221 |
BMS-986172
MGAT2 inhibitor
|
BMS-986172 is a highly potent, selective monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with IC50 of 4.6 nM (human MGAT2). |
| PC-20386 |
AZD7687
DGAT1 inhibitor
|
AZD7687 (AZD-7687) is a potent, selective DGAT1 inhibitor with IC50 of 80 nM (hDGAT1), >400-fold selectivity over hACAT1. |
| PC-20385 |
AZD3988
DGAT-1 inhibitor
|
AZD3988 (AZD-3988) is a potent, selective DGAT-1 inhibitor with IC50 of 0.6/0.5/1.1 nM for human/mouse/rat DGAT-1, does not inhibit DGAT-2 at 10 uM. |
| PC-73119 |
PF-06427878
DGAT2 inhibitor
|
PF-06427878 is a potent, selective, oral DGAT2 inhibitor with IC50 of 99/202 nM for human/rat DGAT2, >470-fold selectivity over DGAT1 and MGAT1/2/3. |
