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Chemical Structure : PF-07284892
CAS No.: 2498597-94-5
Catalog No.: PC-72611Not For Human Use, Lab Use Only.
PF-07284892 (ARRY-558) is a potent, selective allosteric SHP2 inhibitor with IC50 of 21 nM, has 1,000-fold selectivity for SHP2 over 21 other phosphatases, including the closely related SHP1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $238 | In stock | |
| 25 mg | $388 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | Get quote |
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| M.Wt | 439.96 | |
| Formula | C21H22ClN7S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-1'-(6-((3-amino-2-chlorophenyl)thio)-1,2,4-triazin-3-yl)-1,3-dihydrospiro[indene-2,4'-piperidin]-1-amine |
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1. Drilon A, et al. Cancer Discov. 2023 Aug 4;13(8):1789-1801.
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