PF-3837 | MPS1/TTK inhibitor | Probechem Biochemicals

Chemical Structure : PF-3837

Catalog No.: PC-21558Not For Human Use, Lab Use Only.

PF-3837 is a potent, highly-selective Mps1 (TTK) inhibitor with Ki of 0.33 nM, potently inhibit Mps1 in MDA-MB-468 tumor cells with IC50 of 5.5 nM.

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Biological Activity

PF-3837 is a potent, highly-selective Mps1 (TTK) inhibitor with Ki of 0.33 nM, potently inhibit Mps1 in MDA-MB-468 tumor cells with IC50 of 5.5 nM.

M.Wt	422.49
Formula	C21H26N8O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((1-hydroxy-2-methylpropan-2-yl)amino)-2-((2-methyl-6-morpholinopyridin-3-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

1. Ricardo Martinez, et al. PLoS One. 2015 Sep 23;10(9):e0138616.