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Chemical Structure : PF-CBP1
CAS No.: 1962928-21-7
Catalog No.: PC-70031Not For Human Use, Lab Use Only.
PF-CBP1 is a potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $218 | In stock | |
| 100 mg | Get quote |
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PF-CBP1 is a potent, highly selective CBP/p300 bromodomains inhibitor with IC50 of 125 nM and 363 nM, respectively.
PF-CBP1 displays >100-fold selectivity for the bromodomain of CBP over those of BRD4 and a panel of other proteins.
PF-CBP1 reduces the expression of inflammatory cytokines by LPS-stimulated primary macrophages, also suppresses the expression of RGS4 in primary cortical neurons.
| M.Wt | 488.6 | |
| Formula | C29H36N4O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(4-propoxyphenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine |
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1. Chekler EL, et al. Chem Biol. 2015 Dec 17;22(12):1588-96.
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