PF 1022A |CAS:133413-70-4 Probechem Biochemicals

Chemical Structure : PF 1022A

CAS No.: 133413-70-4

PF 1022A (PF1022A;PF-1022A)

Catalog No.: PC-43003Not For Human Use, Lab Use Only.

PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes.

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5 mg	$380	In stock
25 mg	$980	In stock
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Biological Activity

PF1022A is an anthelmintic cyclodepsipeptide of fungal origin, binds to the latrophilin-like transmembrane receptor important for pharyngeal pumping in nematodes; binds to GABA receptors, which might contribute to the anthelmintic effect, like other cyclodepsipeptides, PF1022A acts as an ionophore.

Physicochemical Properties

M.Wt	949.1794
Formula	C52H76N4O12
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 43 mg/mL
Chemical Name/SMILES	Cyclo[(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl-(αR)-α-hydroxybenzenepropanoyl-N-methyl-L-leucyl-(2R)-2-hydroxypropanoyl-N-methyl-L-leucyl]

References

1. Sasaki T, et al. J Antibiot (Tokyo). 1992 May;45(5):692-7.

2. Dornetshuber R, et al. Biochem Pharmacol. 2009 Apr 15;77(8):1437-44.

3. Chen W, et al. Parasitol Res. 1996;82(2):97-101.

4. von Samson-Himmelstjerna G, et al. Parasitol Res. 2000 Mar;86(3):194-9.

PF 1022A (PF1022A;PF-1022A)

Biological Activity

Physicochemical Properties

References

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