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Chemical Structure : PFI-5
Catalog No.: PC-73054Not For Human Use, Lab Use Only.
PFI-5 a highly biochemically potent, selective, and cell-active SMYD2 chemical probe with IC50 of 8 nM.
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PFI-5 a highly biochemically potent, selective, and cell-active SMYD2 chemical probe with IC50 of 8 nM.
PFI-5 inhibits p53 methylation in MCF7 cells with EC50 of 1.3 uM, with no toxicity.
| M.Wt | 501.679 | |
| Formula | C29H39N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Taylor AP, et al. J Med Chem. 2019 Sep 12;62(17):7669-7683.
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