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PG-116800

Chemical Structure : PG-116800

CAS No.: 291533-11-4

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PG-116800 (PG116800)

Catalog No.: PC-72040Not For Human Use, Lab Use Only.

PG-116800 is a selective, oral matrix metalloproteinase (MMPs) inhibitor with significant antiremodeling effects in animal models of MI and ischemic heart failure.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PG-116800 is a selective, oral matrix metalloproteinase (MMPs) inhibitor with significant antiremodeling effects in animal models of MI and ischemic heart failure.

    Physicochemical Properties

    M.Wt 501.55
    Formula C24H27N3O7S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-((4-(4-methoxybenzamido)phenyl)sulfonamido)-6-morpholinohex-4-ynoic acid

    References

    1. Sydlowski D, et al. J Am Coll Cardiol. 2006 Jul 4;48(1):15-20. 

    2. Daniel P Becker, et al. J Med Chem. 2010 Sep 23;53(18):6653-80.

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