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Chemical Structure : PHTPP
Catalog No.: PC-60267Not For Human Use, Lab Use Only.
A potent, selective antagonist of estrogen ERβ receptor.
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A potent, selective antagonist of estrogen ERβ receptor; exhibits 36-fold selective for ERβ, and is fully effective as an ERα antagonist, while exhibiting no significant agonism on ERβ or Erα; enhances SKOV3 and OV2008 ovarian cancer cell growth in in vitro assays.
| M.Wt | 423.3 | |
| Formula | C20H11F6N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Compton DR, et al. J Med Chem. 2004 Nov 18;47(24):5872-93.
2. Chan KK, et al. J Endocrinol. 2014 May 12;221(2):325-36.
3. Kajta M, et al. Neuroscience. 2013 May 15;238:345-60.
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