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PI5P4K inhibitor 30

Chemical Structure : PI5P4K inhibitor 30

CAS No.: 2471969-07-8

PI5P4K inhibitor 30

Catalog No.: PC-38274Not For Human Use, Lab Use Only.

PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PI5P4K inhibitor 30 is a highly selective pan-PI5P4K covalent inhibitor with IC50 of 1.3/9.9 uM against PI5P4Kα/β, inhibits PI5P4Kγ by 22% at 1 uM.

    Physicochemical Properties

    M.Wt 545.647
    Formula C32H31N7O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-4-(4-(dimethylamino)but-2-enamido)-N-(3-((7-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)benzamide

    References

    1. Theresa D Manz, et al. ACS Med Chem Lett. 2019 Nov 3;11(3):346-352.

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