PI5P4Kγ inhibitor 40

Chemical Structure : PI5P4Kγ inhibitor 40

Catalog No.: PC-38270Not For Human Use, Lab Use Only.

PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6.

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Biological Activity

PI5P4Kγ inhibitor 40 is a selective, non-ATP-competitive, allosteric inhibitor of PI5P4Kγ with pIC50 of 6.2, does not inhibit PI5P4Kα/β with pIC50<4.6.

Physicochemical Properties

M.Wt	357.461
Formula	C22H23N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-isopropylphenyl)-5-methyl-N-(pyridin-2-ylmethyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine

References

1. Helen K Boffey, et al. J Med Chem. 2022 Feb 11. doi: 10.1021/acs.jmedchem.1c01819.

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