PKM2 aggregates inhibitor K27 | PKM2 aggregates inhibitor

Chemical Structure : PKM2 aggregates inhibitor K27

PKM2 aggregates inhibitor K27 (PKM2 aggregate-dissolving compound K27)

Catalog No.: PC-22681Not For Human Use, Lab Use Only.

PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

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Biological Activity

Physicochemical Properties

M.Wt	530.65
Formula	C24H23FN4O3S3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	pyridin-3-ylmethyl 4-(4-((4-fluorophenyl)sulfonamido)benzoyl)piperazine-1-carbodithioate

References

1. Juntao Bie, et al. Nat Commun. 2024 Jul 9;15(1):5761.

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PKM2 aggregates inhibitor K27 (PKM2 aggregate-dissolving compound K27)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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