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PKM2 aggregates inhibitor K27

Chemical Structure : PKM2 aggregates inhibitor K27

CAS No.: 2602406-58-4

PKM2 aggregates inhibitor K27 (PKM2 aggregate-dissolving compound K27)

Catalog No.: PC-22681Not For Human Use, Lab Use Only.

PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PKM2 aggregates inhibitor K27 is a small molecule capable of dissolving PKM2 aggregates and alleviating senescence, restores PKM2 enzymatic activity and glycolytic flux, delays aging of naturally and prematurely aged mice.

Physicochemical Properties

M.Wt 530.65
Formula C24H23FN4O3S3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

pyridin-3-ylmethyl 4-(4-((4-fluorophenyl)sulfonamido)benzoyl)piperazine-1-carbodithioate

References

1. Juntao Bie, et al. Nat Commun. 2024 Jul 9;15(1):5761.

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