PNPLA4-IN-1 |CAS:2098890-86-7 Probechem Biochemicals

Chemical Structure : PNPLA4-IN-1

PNPLA4-IN-1

Catalog No.: PC-62861Not For Human Use, Lab Use Only.

PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 (patatin-like phospholipase domain-containing protein 4) inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM.

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Biological Activity

PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 (patatin-like phospholipase domain-containing protein 4) inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM.

Physicochemical Properties

M.Wt	375.439
Formula	C19H21NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	7-methoxy-2-(5-phenylpentyl)benzo[e][1,4,3]oxathiazin-3(2H)-one 1,1-dioxide

References

1. Kornahrens AF, et al. J Am Chem Soc. 2017 May 24;139(20):7052-7061.

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PNPLA4-IN-1

Biological Activity

Physicochemical Properties

References

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