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PNPLA4-IN-1

Chemical Structure : PNPLA4-IN-1

CAS No.: 2098890-86-7

PNPLA4-IN-1

Catalog No.: PC-62861Not For Human Use, Lab Use Only.

PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 (patatin-like phospholipase domain-containing protein 4) inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PNPLA4-IN-1 is a potent, selective, and irreversible PNPLA4 (patatin-like phospholipase domain-containing protein 4) inhibitor with IC50 of 1.8 uM (separated membrane proteome fraction), shows in-cell inhibition of PNPLA4 with IC50 of 11.7 uM.

    Physicochemical Properties

    M.Wt 375.439
    Formula C19H21NO5S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-methoxy-2-(5-phenylpentyl)benzo[e][1,4,3]oxathiazin-3(2H)-one 1,1-dioxide

    References

    1. Kornahrens AF, et al. J Am Chem Soc. 2017 May 24;139(20):7052-7061.

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