PPARα activator compound 3 |CAS:1011399-77-1 Probechem Biochemicals

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Chemical Structure : PPARα activator compound 3

PPARα activator compound 3

Catalog No.: PC-35153Not For Human Use, Lab Use Only.

PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo.
PPARα activator compound 3 reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.

Physicochemical Properties

M.Wt	339.37
Formula	C19H18FN3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

References

1. Tachibana K, et al. J Biol Chem. 2018 May 15. pii: jbc.RA118.002077.

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