PPARα agonist A229 | PPARα agonist | Probechem Biochemicals

Chemical Structure : PPARα agonist A229

PPARα agonist A229 (A229)

Catalog No.: PC-22731Not For Human Use, Lab Use Only.

A229 is a potent, selective peroxisome proliferator-activated receptor alpha (PPARα) agonist with EC50 of 590 nM, shows subtype selectivity for PPARα in luciferase-based cell assay.

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Biological Activity

A229 is a potent, selective peroxisome proliferator-activated receptor alpha (PPARα) agonist with EC50 of 590 nM, shows subtype selectivity for PPARα in luciferase-based cell assay.

Physicochemical Properties

M.Wt	339.34
Formula	C20H15F2NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-fluoro-5-(((4'-fluoro-[1,1'-biphenyl]-4-yl)methyl)amino)benzoic acid

References

1. Julia J Lee, et al. Design, Synthesis, and Structure-Activity Relationships of Biaryl Anilines as Subtype-Selective PPAR-alpha Agonists. ACS Med Chem Lett. 2023 May 23;14(6):766-776.

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PPARα agonist A229 (A229)

Biological Activity

Physicochemical Properties

References

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