PPTD free base

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Chemical Structure : PPTD free base

Catalog No.: PC-25882Not For Human Use, Lab Use Only.

PPTD free base is the first selective small-molecule inhibitor of membrane-bound metal transporter ZIP14/SLC39A14, efficiently blocks ZIP14-mediated uptake of zinc, iron, manganese and cadmium, while sparing the closely related transporter ZIP8/SLC39A8.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	335.45
Formula	C21H25N3O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	8-phenethyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

References

1. Takafumi Hara, et al. bioRxiv. [Preprint]. 2025 Oct 23:2025.10.23.682519.

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PPTD free base

Biological Activity

Physicochemical Properties

References

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