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PPZ2

Chemical Structure : PPZ2

CAS No.: 896203-18-2

PPZ2

Catalog No.: PC-25781Not For Human Use, Lab Use Only.

PPZ2 is a selective activator of TRPC3/TRPC6/TRPC7, activates DAG-activated TRPC3/TRPC6/TRPC7 channels, promotes neurite outgrowth and neuronal survival via downstream Ca2+-dependent signals.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PPZ2 is a selective activator of TRPC3/TRPC6/TRPC7, activates DAG-activated TRPC3/TRPC6/TRPC7 channels, promotes neurite outgrowth and neuronal survival via downstream Ca2+-dependent signals.

Physicochemical Properties

M.Wt 367.49
Formula C22H29N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-N-(2-ethoxyphenyl)acetamide

References

1. Sawamura S, et al. Mol Pharmacol. 2016 Mar;89(3):348-63.

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