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Chemical Structure : PR-893
Catalog No.: PC-60964Not For Human Use, Lab Use Only.
PR-893 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
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PR-893 is a potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
| M.Wt | 478.546 | |
| Formula | C23H34N4O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Parlati F, et al. Blood. 2009 Oct 15;114(16):3439-47.
2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
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