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Chemical Structure : PRG-A01
Catalog No.: PC-73386Not For Human Use, Lab Use Only.
PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression.
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PRG-A01 is a chemical inhibitor against SOD1 misfolding and aggregation, inhibits the neuronal cell death caused by mutant-SOD1 overexpression.
PRG-A01 inhibited the aggregation formed between SOD1 and TDP-43.
PRG-A01 demonstrated therapeutic effect of PRG-A01 in vivo, ameliorated motor neuron regression, movement disorder, and prolonged life span in SOD1G93A-Tg ALS mouse model.
| M.Wt | 422.43 | |
| Formula | C24H22O7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tae-Gyun Woo, et al. Commun Biol. 2021 Dec 15;4(1):1397.
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