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PSAC inhibitor compound 1

Chemical Structure : PSAC inhibitor compound 1

CAS No.:

PSAC inhibitor compound 1

Catalog No.: PC-24699Not For Human Use, Lab Use Only.

PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PSAC inhibitor compound 1 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.3.

Physicochemical Properties

M.Wt 437.92
Formula C24H24ClN3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-chloro-N1-isopropyl-N3-(4-(6-methoxypyridin-3-yl)benzyl)isophthalamide

References

1. Molina I, et al. Cell Chem Biol. 2025 May 21:S2451-9456(25)00136-9.

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