PSAC inhibitor compound 2

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Chemical Structure : PSAC inhibitor compound 2

Catalog No.: PC-24700Not For Human Use, Lab Use Only.

PSAC inhibitor compound 2 is a small molecule inhibitor of plasmodial surface anion channel (PSAC), targets the PSAC component CLAG3 and inhibits malaria solute transport by PSAC, protects trophozoite-infected RBCs from sorbitol-mediated lysis with pIC50 of 7.9.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	347.42
Formula	C20H21N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1H-indol-2-yl)((2s,4r)-2-(pyrimidin-4-ylamino)-6-azaspiro[3.4]octan-6-yl)methanone

References

1. Molina I, et al. Cell Chem Biol. 2025 May 21:S2451-9456(25)00136-9.

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