PSB-1115 | A2B antagonist | Probechem Biochemicals

Chemical Structure : PSB-1115

CAS No.: 152529-79-8

PSB-1115 (PSB1115)

Catalog No.: PC-20546Not For Human Use, Lab Use Only.

PSB-1115 (PSB1115) is a potent, selective adenosine A2B receptor antagonist with binding Ki of 53.4 nM (recombinant human A2B receptor), 40- and 400-fold selectivity over A1 and A2A receptors.

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Biological Activity

PSB-1115 (PSB1115) is a potent, selective adenosine A2B receptor antagonist with binding Ki of 53.4 nM (recombinant human A2B receptor), 40- and 400-fold selectivity over A1 and A2A receptors.

Physicochemical Properties

M.Wt	350.35
Formula	C14H14N4O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonic acid

References

1. Godfrey L, et al. Eur J Pharmacol. 2006 Feb 15;531(1-3):80-6.

2. Yan L, et al. J Med Chem. 2004 Feb 12;47(4):1031-43.

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PSB-1115 (PSB1115)

Biological Activity

Physicochemical Properties

References

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