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PSB-16434

Chemical Structure : PSB-16434

CAS No.: 2189700-02-3

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PSB-16434 (PSB16434)

Catalog No.: PC-21649Not For Human Use, Lab Use Only.

PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PSB-16434 is a highly potent, Gi pathway-selective GPR84 agonist with cAMP EC50 of 7.1 nM, 79-fold selective over β-arrestin-2 recruitment activity.
    PSB-16434 shows selectivity over other free fatty acid-activated receptors.

    Physicochemical Properties

    M.Wt 265.70
    Formula C12H12ClN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-((4-chlorophenethyl)amino)pyrimidine-2,4(1H,3H)-dione

    References

    1. Thanigaimalai Pillaiyar, et al. ACS Omega. 2018 Mar 31;3(3):3365-3383.

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