Chemical Structure : PSB-22034
Catalog No.: PC-21318Not For Human Use, Lab Use Only.
PSB-22034 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 11.2 nM/32.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
PSB-22034 is a potent, selective agonist of MAS-related Gq protein-coupled receptor X4 (MRGPRX4) with EC50 of 11.2 nM/32.0 nM in Ca2+ assay/β-arrestin assays (variant 83S), respectively.
PSB-22034 shows high selectivity over the other MRGPRX subtypes, MRGPRX1, -2, and -3.
PSB-22034 is a promising tool compound for exploring the potential of MRGPRX4 as a future drug target.
M.Wt | 460.43 | |
Formula | C21H25N4O6P | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Marx D, et al. J Med Chem. 2023 Nov 15. doi: 10.1021/acs.jmedchem.3c01013.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright