PT-13

Chemical Structure : PT-13

Catalog No.: PC-27133Not For Human Use, Lab Use Only.

PT-13 is a brain-penetrant small-molecule tau disaggregant inhibiting tau seeding and disaggregating fibrils, reduces tau pathology while preserving behavioral function, proteasome capacity, and synaptic integrity in tauopathy mouse model.

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Biological Activity

Physicochemical Properties

M.Wt	290.28
Formula	C17H10N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-cyanophenyl)-2-oxo-2H-chromene-3-carboxamide

References

1. Mostowfi N, et al. bioRxiv [Preprint]. 2026 Jun 12:2026.06.09.731185.

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PT-13

Biological Activity

Physicochemical Properties

References

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