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PT-179

Chemical Structure : PT-179

CAS No.: 2924858-25-1

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PT-179 (PT179)

Catalog No.: PC-21965Not For Human Use, Lab Use Only.

PT-179 is a selective molecular glue and thalidomide derivative, binds CRBN with a Kd of 587 nM, does not induce degradation of known pomalidomide neosubstrates.

Packing Price Stock Quantity
5 mg $58 In stock
10 mg $88 In stock
25 mg $158 In stock
50 mg $248 In stock
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Purity & Documentation Purity: 99.9% (HPLC) Select Batch:

Biological Activity

PT-179 is a selective molecular glue and thalidomide derivative, binds CRBN with a Kd of 587 nM, does not induce degradation of known pomalidomide neosubstrates.

Physicochemical Properties

M.Wt 343.34
Formula C17H17N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2,6-dioxopiperidin-3-yl)-5-morpholinoisoindoline-1,3-dione

References

1. Mercer JAM, et al. Science. 2024 Mar 15;383(6688):eadk4422.

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