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PTP1B-IN-1

Chemical Structure : PTP1B-IN-1

CAS No.: 612530-44-6

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PTP1B-IN-1 (PTP1B inhibitor 1)

Catalog No.: PC-42696Not For Human Use, Lab Use Only.

PTP1B-IN-1 is a 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for design of protein tyrosine phosphatase-1B (PTP1B) inhibitor, shows weak inhibition for PTP1B with IC50 of 1.6 mM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PTP1B-IN-1 is a 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for design of protein tyrosine phosphatase-1B (PTP1B) inhibitor, shows weak inhibition for PTP1B with IC50 of 1.6 mM.

Physicochemical Properties

M.Wt 212.2257
Formula C8H8N2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 38 mg/mL
Chemical Name/SMILES

1,2,5-Thiadiazolidin-3-one, 5-phenyl-, 1,1-dioxide

References

1. Black E, et al. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7.

2. Vintonyak VV, et al. Bioorg Med Chem. 2011 Apr 1;19(7):2145-55.

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