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Chemical Structure : PTP1B-IN-5b
Catalog No.: PC-62844Not For Human Use, Lab Use Only.
PTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM.
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PTP1B-IN-5b is a potent protein tyrosine phosphatase PTP1B inhibitor with IC50 of 5.25 uM.
PTP1B-IN-5b shows remarkable cytotoxic activity at 0.09 uM of IC50 against the MCF-7 cell line.
PTP1B-IN-5b also showed potential anticancer activity against MCF-7 (IC50=2.22 uM) and HepG2 (IC50=0.72 uM) cell lines as well as PTP1B inhibitory activity with IC50 of 6.37 uM.
| M.Wt | 417.479 | |
| Formula | C24H19NO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gulipalli KC, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3558-3564.
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