Chemical Structure : PTP1B inhibitor BBR
CAS No.:
765317-72-4
PTP1B inhibitor BBR
(PTP1B-IN-4, PTP1B inhibitor compound 2)
Catalog No. : PC-20469Not For Human Use, Lab Use Only.
PTP1B inhibitor BBR is a selective, non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B with IC50 of 8 uM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2046901
Biological Activity
PTP1B inhibitor BBR is a selective, non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B with IC50 of 8 uM.
Physicochemical Properties
M.Wt
741.44
Formula
C26H19Br2N3O7S3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide
References
1. Wiesmann, C., et al. Nature Structural & Molecular Biology,
2. Jin, T., et al. Scientific Reports
3. Anika J Friedman, et al. J Phys Chem B
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