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Chemical Structure : PTP1B inhibitor BBR
CAS No.: 765317-72-4
Catalog No.: PC-20469Not For Human Use, Lab Use Only.
PTP1B inhibitor BBR is a selective, non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B with IC50 of 8 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $188 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PTP1B inhibitor BBR is a selective, non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B with IC50 of 8 uM.
PTP1B inhibitor BBR exhibit selectivity for PTP1B over the related phosphatase leukocyte antigen-related protein, LAR (IC50 > 500 uM), TC-PTP and PTP1B.
PTP1B inhibitor BBR enhances insulin signaling in cells.
| M.Wt | 741.44 | |
| Formula | C26H19Br2N3O7S3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide |
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1. Wiesmann, C., et al. Nature Structural & Molecular Biology, 2004. 11(8), 730–737.
2. Jin, T., et al. Scientific Reports, 2016. 6(1).
3. Anika J Friedman, et al. J Phys Chem B. 2022 Oct 27;126(42):8427-8438.
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