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PTP4A3 inhibitor BR-1

Chemical Structure : PTP4A3 inhibitor BR-1

CAS No.: 893449-38-2

PTP4A3 inhibitor BR-1

Catalog No.: PC-22858Not For Human Use, Lab Use Only.

PTP4A3 inhibitor BR-1 is a specfiic inhibitor of PTP4A3 (PRL-3, phosphatase of regenerating liver-3) with IC50 of 1.1 uM, selective over other 10 phosphatases, inhibits the migration and invasion of metastatic cancer cells.

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Biological Activity

PTP4A3 inhibitor BR-1 is a specfiic inhibitor of PTP4A3 (PRL-3, phosphatase of regenerating liver-3) with IC50 of 1.1 uM, selective over other 10 phosphatases, inhibits the migration and invasion of metastatic cancer cells.

Physicochemical Properties

M.Wt 485.21
Formula C17H11Br2NO2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-5-(5-bromo-2-((2-bromobenzyl)oxy)benzylidene)-2-thioxothiazolidin-4-one

References

1. Ahn JH, et al. Bioorg. Med. Chem. Lett. 2013;23:3769.

2. Garam Min, et al. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3769-74.

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