PU-HZ151 | HSP90 inhibitor | Probechem Biochemicals

Chemical Structure : PU-HZ151

CAS No.: 1000999-96-1

PU-HZ151 (Icapamespib, PU HZ151)

Catalog No.: PC-72711Not For Human Use, Lab Use Only.

PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.

Packing	Price	Stock
2 mg	$188	In stock
5 mg	$328	In stock
10 mg	$528	In stock
25 mg	$898	In stock
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Biological Activity

Physicochemical Properties

M.Wt	526.398
Formula	C19H23IN6O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine

References

1. Bolaender A, et al. Nat Commun. 2021 Aug 3;12(1):4669.

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PU-HZ151 (Icapamespib, PU HZ151)

Biological Activity

Physicochemical Properties

References

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