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Chemical Structure : PU-HZ151
CAS No.: 1000999-96-1
Catalog No.: PC-72711Not For Human Use, Lab Use Only.
PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $188 | In stock | |
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
| 25 mg | $898 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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PU-HZ151 (Icapamespib, PU HZ151) is a specific CNS-directed epichaperome probe, with selectivity for epichaperomes over the individual chaperome membersm, inhibits HSP90 with EC50 of 5 nM in the FP assays.
| M.Wt | 526.398 | |
| Formula | C19H23IN6O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(6-iodo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-6-amine |
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1. Bolaender A, et al. Nat Commun. 2021 Aug 3;12(1):4669.
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