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PZ-II-029

Chemical Structure : PZ-II-029

CAS No.: 164025-44-9

PZ-II-029

Catalog No.: PC-25018Not For Human Use, Lab Use Only.

PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.

Physicochemical Properties

M.Wt 321.34
Formula C18H15N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-Methoxy-2-(4-methoxyphenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one

References

1. Fan PC, et al. Neuropharmacology. 2018 Sep 15;140:1-13.

2. Chiou LC, et al. Br J Pharmacol. 2018 Jun;175(12):2414-2427.

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