Chemical Structure : PZ-II-029
CAS No.: 164025-44-9
Catalog No.: PC-25018Not For Human Use, Lab Use Only.
PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.
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PZ-II-029 is a selective, positive allosteric modulator (PAM) of α6 subunit-containing GABAA receptor, potentiates α6β3γ2S GABAA receptor‐mediated GABA currents.
M.Wt | 321.34 | |
Formula | C18H15N3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
7-Methoxy-2-(4-methoxyphenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one |
1. Fan PC, et al. Neuropharmacology. 2018 Sep 15;140:1-13.
2. Chiou LC, et al. Br J Pharmacol. 2018 Jun;175(12):2414-2427.
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