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Chemical Structure : Pannexin-1 inhibitor 15b
Catalog No.: PC-72399Not For Human Use, Lab Use Only.
Panx-1 blocker 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.
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Pannexin-1 inhibitor 15b is a large-pore channel pannexin 1 (Panx1) inhibitor with IC50 of 0.8 uM.
Pannexin-1 inhibitor 15b (administered intrathecally, 1 nM) completely reverted the hypersensitivity in the mouse model of oxaliplatin-induced neuropa.
| M.Wt | 508.501 | |
| Formula | C25H20N2O8S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Letizia Crocetti, et al. Eur J Med Chem. 2021 Nov 5;223:113650.
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