Parabulin

Chemical Structure : Parabulin

Catalog No.: PC-38234Not For Human Use, Lab Use Only.

Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.

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Biological Activity

Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.
Parabulin specifically inhibits growth of protozoan parasites (EC50=6.5 uM, apicomplexan parasite Toxoplasma gondii) and inhibits their microtubule formation in vitro.

Physicochemical Properties

M.Wt	387.432
Formula	C21H25NO6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(3,4-dimethoxyphenyl)-N-(3,4,5-trimethoxybenzyl)acrylamide

References

1. Natacha Gaillard, et al. EMBO Mol Med. 2021 Nov 8;13(11):e13818.

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Parabulin

Biological Activity

Physicochemical Properties

References

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