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Parabulin

Chemical Structure : Parabulin

CAS No.: 2766184-58-9

Parabulin

Catalog No.: PC-38234Not For Human Use, Lab Use Only.

Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.

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    Biological Activity

    Parabulin is a novel potent, parasite-specific tubulin inhibitor, inhibits growth of parasites while displaying no effects on human cells.
    Parabulin specifically inhibits growth of protozoan parasites (EC50=6.5 uM, apicomplexan parasite Toxoplasma gondii) and inhibits their microtubule formation in vitro.

    Physicochemical Properties

    M.Wt 387.432
    Formula C21H25NO6
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-3-(3,4-dimethoxyphenyl)-N-(3,4,5-trimethoxybenzyl)acrylamide

    References

    1. Natacha Gaillard, et al. EMBO Mol Med. 2021 Nov 8;13(11):e13818.

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